Intermittent self-catheterisation (ISC) is used in everyday practice for bladder dysfunction. This study from Southampton, UK presents a Cochrane review of different catheter designs, user satisfaction and incidence of urinary tract infection (UTI), etc. The following factors were looked at: 1) single use vs. multiple use catheters, 2) hydrophilic coated vs. prelubricated / uncoated, 3) sterile technique vs. clean. Thirty-one trials (13 randomised controlled trials and 18 randomised crossover trials) were studied. There is a wide difference in studies and follow-up, etc. In summary, the current evidence is weak. It has not been established whether UTI and haematuria etc. are related to sterile or clean techniques. For the time being a patient’s choice will depend on personal preference, cost, portability and ease of user. Further clinical trials are necessary.