Talk to many urologists and the axiom is “you are more likely to die with prostate cancer than from it”. This study was conducted on Danish men between 1995 and 2011. The observations are: 1) Cumulative prostate cancer – specific mortality was 25.6% vs. 50.5% mortality from other causes; 2) In men with initial benign biopsy, incidence of prostate cancer, specific mortality was 5.2% vs. 59.9% from other causes; 3) In men with prostate specific antigen (PSA) of 10 microgram/L or less and benign biopsy, mortality was only 0.7%. So prostate cancer is perhaps not such a dreaded disease after all. 

Risk of prostate cancer diagnosis and mortality in men with a benign initial transrectal ultrasound-guided biopsy set: a population-based study.
Klemann N, Røder MA, Helgstrand JT, et al.
THE LANCET ONCOLOGY
2017;18(2):221-229.
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Arun K Sharma

West Herts NHS Trust (Watford General Hospital)

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