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Upper urinary tract urothelial cell carcinoma

7 January 2021 | | Urologic Oncology
Case 1 A 64-year-old man presents to the haematuria clinic with visible haematuria, on a background of a 40 pack-year smoking history and family history of bowel cancer in his sister at the age of 48. A CT was performed...

Prostate Cancer Focus

The ‘Prostate Cancer Focus 2021’ supplement from Urology News collates a range of articles covering the latest in the management of prostate cancer. The last year has seen plenty of innovation in the management of the condition, while the all-consuming...

The assessment and medical treatment of LUTS secondary to BPH

1 November 2016 | Functional Urology
The term benign prostatic hyperplasia (BPH) describes prostate enlargement due to non-cancerous processes. Several aetiological mechanisms are involved, including hormonal and vascular alterations; abnormal regulation of apoptosis; and prostatic inflammation, which may stimulate cellular proliferation. With ageing, prostate enlargement can...

Biomarkers in prostate cancer detection

1 July 2018 | | Basic Science Research, Technological Developments, Urologic Oncology
Prostate cancer (PCa) is the second most common cancer in men with an estimated prevalence of 1.1 million worldwide in 2012. This heterogeneous disease resulted in approximately 307,000 deaths, making it the fifth leading cause of cancer-related death in men...

The importance of active investigation and follow-up in bladder injury

11 July 2023 | | Trauma and Emergency Urology
Bladder injury (BI) is uncommon, and patients are typically managed by large multidisciplinary teams, dealing concomitantly with other injuries or diagnoses. BI can be categorised by cause (traumatic vs. iatrogenic) or anatomical location (intraperitoneal vs. extraperitoneal), requiring differing approaches to...

Sperm selection techniques in assisted reproductive technologies: state of the ART?

4 May 2023 | | Andrology, Technological Developments
Infertility is the inability to achieve pregnancy following one year of regular, unprotected intercourse (in the fertile phase of the menstrual cycle). Infertility is a common problem that affects between 7 and 15% of couples worldwide, with male factor infertility...

Prostate cancer

1 July 2015 | | Urologic Oncology
Case 1 What is prostate specific antigen (PSA) and what is its function? According to the ERSPC Trial (at 13 years), what was the number needed to screen and diagnosed to prevent one prostate cancer death and what was the...

Read all about it Jul/Aug 2014

1 July 2014 | Andrology, Basic Science Research, Endourology and Stones, Functional Urology, Infection, Neurourology, Paediatric Urology, Reconstructive Urology, Technological Developments, Trauma and Emergency Urology, Urologic Oncology, Uroradiology
It can be awkward when a patient asks you about a report in their favourite tabloid detailing an amazing research breakthrough or a ‘cutting-edge’ new treatment / test and you don’t know what they are talking about! So this section...

The conservative assessment and treatment of mixed urinary and anal incontinence in women: a multidisciplinary approach

1 September 2019 | | Functional Urology, Neurourology
Mixed urinary incontinence Urinary incontinence (UI) is considered to be a highly prevalent condition; however, depending upon the definitions used, actual reported prevalence rates can vary significantly. The International Consultation on Incontinence (ICI) review [1], reported unadjusted prevalence estimates for...

The process of medical innovation – evolving trends and future perspectives

5 May 2021 | | Technological Developments
In 2018 the United Kingdom Government spending on healthcare totalled almost £166 billion. Of this approximately 65% was attributed to providing curative or rehabilitation therapy, with health-related long-term care and provision of goods accounting for 25%. The remaining was accredited...

Metastatic spinal cord compression – a review

1 March 2014 | | Trauma and Emergency Urology, Urologic Oncology
Introduction Metastatic spinal cord compression (MSCC) is an oncological emergency that, unless diagnosed early and treated appropriately, can lead to significant morbidity and mortality, including paralysis and bladder and bowel dysfunction. MSCC can be defined as spinal cord or cauda...

Clear cell urothelial carcinoma: a highly aggressive morphological variant in the bladder and upper urinary tract

2 November 2023 | | Urologic Oncology
Clear cell urothelial carcinoma (CCUC) is a rare morphological variant of transitional cell carcinoma (TCC). It can occur anywhere along the urothelial tract and is characterised histologically by high grade carcinoma with an abundance of clear, glycogen-rich cytoplasm [1]. Alternative...