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PDE5I in LUTS – how do they work – no proof yet

1 September 2014 | | Basic Science Research, Endourology and Stones, Functional Urology
Phosphodiesterase type 5 (PDE5) inhibitors used in erectile dysfunction (ED) have been shown to improve lower urinary tract symptoms (LUTS) as well. The mechanism is not well understood. One of the hypotheses for benign prostatic hyperplasia (BPH) – LUTS is...

Intravesical cytosine arabinoside + Mitomycin C for bladder cancer – is it beneficial?

12 October 2022 | | Urologic Oncology | #BladderCancer, #blcsm, cytosine arabinoside, intravesical therapy, mitomycin C, non-muscle-invasive bladder cancer, randomised trial, #uroonc, urinary pH
Mitomycin C (MMC) is often used as an intravesical therapy for low / intermediate risk non-muscle invasive bladder cancer. This randomised controlled trial (RCT) was designed to assess the safety and efficacy of MMC + cytosine arabinoside (Ara-C). Ara-C was...
The Journal of Urology cover image.

Hypospadias – how long should follow-up be?

3 February 2023 | | Paediatric Urology
The optimal duration of follow-up following childhood hypospadias repair (to detect complications) is ill-defined. Several surgeons recommend it to include assessment during puberty. Some may worry that ‘rapid penile growth’, ‘erectile forces’ and ‘sexual activity’ could potentially stress previously successful...

Nocturia – the Cinderella of lower urinary tract symptoms

1 March 2014 | | Functional Urology
Nocturia is defined as waking during the night (at least once) to urinate. The important part of the definition relates to the necessity of sleep to precede the episode (although whether sleep must follow the episode is less clear). The...

Kidney stones in pregnancy

2 November 2023 | | Endourology and Stones
Case 1 A 28-year-old female, 19 weeks pregnant, presents with severe left loin pain. There is no past medical history of note. Blood tests show a white cell count of 14.1x109/L and creatinine of 56umol/L. An ultrasound scan (USS) reports...

Sperm selection techniques in assisted reproductive technologies: state of the ART?

4 May 2023 | | Andrology, Technological Developments
Infertility is the inability to achieve pregnancy following one year of regular, unprotected intercourse (in the fertile phase of the menstrual cycle). Infertility is a common problem that affects between 7 and 15% of couples worldwide, with male factor infertility...

The conservative assessment and treatment of mixed urinary and anal incontinence in women: a multidisciplinary approach

1 September 2019 | | Functional Urology, Neurourology
Mixed urinary incontinence Urinary incontinence (UI) is considered to be a highly prevalent condition; however, depending upon the definitions used, actual reported prevalence rates can vary significantly. The International Consultation on Incontinence (ICI) review [1], reported unadjusted prevalence estimates for...

The how, why and when of bladder washouts: a guide

23 November 2022 | | Functional Urology, Infection
Bladder washouts are a treatment usually employed by the urology team, more often in an inpatient setting, and commonly indicated for haematuria with clot retention and catheter bypassing [1,2]. Bladder washout is a cornerstone of treatment in urology wards, yet...

Read all about it Jul/Aug 2017

1 July 2017 | Andrology, Basic Science Research, Endourology and Stones, Functional Urology, Infection, Neurourology, Paediatric Urology, Reconstructive Urology, Technological Developments, Trauma and Emergency Urology, Uroradiology, Urologic Oncology
It can be awkward when a patient asks you about a report in their favourite tabloid detailing an amazing research breakthrough or a ‘cutting-edge’ new treatment / test and you don’t know what they are talking about! So this section...

Read all about it Jul/Aug 2014

1 July 2014 | Andrology, Basic Science Research, Endourology and Stones, Functional Urology, Infection, Neurourology, Paediatric Urology, Reconstructive Urology, Technological Developments, Trauma and Emergency Urology, Urologic Oncology, Uroradiology
It can be awkward when a patient asks you about a report in their favourite tabloid detailing an amazing research breakthrough or a ‘cutting-edge’ new treatment / test and you don’t know what they are talking about! So this section...

Read all about it Sep/Oct 2017

1 September 2017 | Andrology, Basic Science Research, Endourology and Stones, Functional Urology, Infection, Neurourology, Paediatric Urology, Reconstructive Urology, Technological Developments, Trauma and Emergency Urology, Urologic Oncology, Uroradiology
Read all about it... It can be awkward when a patient asks you about a report in their favourite tabloid detailing an amazing research breakthrough or a ‘cutting-edge’ new treatment / test and you don’t know what they are talking...

Cystoplasty

3 March 2021 | | Reconstructive Urology, Trauma and Emergency Urology
Case 1 A 48-year-old female, having previously had an augmentation ileocystoplasty 10 years ago, has been referred with right loin pain by the emergency department. A venous blood gas is performed shortly after triage with the following values: What is...