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Intravesical GAG replacement therapies for bladder pain syndrome / interstitial cystitis – an update

The barrier function of the glycosaminoglycan (GAG) layer of the urothelium was identified by Parsons in 1975, and intravesical therapies to treat chronic inflammatory conditions of the bladder were developed soon after. However, the active role of the urothelium in...

Nocturia: the debate goes on

This study is from Ghent, Belgium. Nocturia is one of the most bothersome lower urinary tract symptoms affecting both men and women. Key factors to consider in evaluating are nocturnal polyuria (NP) and reduced bladder capacity. NP with low osmolality...

BXTAccelyon becomes global distribution partner for new online prostate MRI self-learning tool to enhance prostate cancer diagnosis

BXTAccelyon, the leading low dose rate (LDR) brachytherapy partner to hospitals and clinics worldwide, and distribution partner for PrecisionPoint™, the...

William Harvey – Not All Heart!

In this series of articles I am going to show you some of the exhibits contained in the Museum of Urology, hosted on the BAUS website (www.baus.org.uk). I expect you will have heard of William Harvey (1578-1657) the 17th Century...

Incontinence, 6th Edition

This is very much a reference text. Comprehensive, authoritative and up-to-date. It deals with every aspect of incontinence from cell biology to clinical examination and from clinical management pathways to the economics of urinary and faecal incontinence. The text is...

Prostate Cancer – Diagnosis and Clinical Management

This rather modest looking paperback actually punches well beyond its humble appearance. There are of course the predictable sub-sections appropriate to any prostate cancer text – but that said this relatively small-volume affair (compared to some of the Goliaths out...

Hard flaccid syndrome

Chronic pelvic pain is defined as pain present below the level of the umbilicus with a duration of more than six months [1,2]. Chronic pelvic pain syndromes (CPPS) are highly prevalent in Western society, affecting both males and females. Studies...

Treatment of varicocele in children and adolescents

Varicocele occur in about 15% of all adolescents. These authors searched Medline, Embase and a number of platforms reporting on varicoses in children and adolescents, including only randomised controlled trials with patients under 21 years. After an initial 198 studies...

Nuptial night tragedy

Case 1 A fit and well 50-year-old gentleman presents to the emergency department with pain and swelling of his penis that started a few hours after he had a shower earlier in the day. On examination, the appearance is as...

In conversation with Nadine Coull

We were delighted to chat to Nadine Coull, the new President of the Royal Society of Medicine Section of Urology about her career so far and aims for the year ahead. Can you tell us a little bit about what...

Non-urothelial bladder malignancies

Case 1 An 80-year-old gentleman presented with a history of visible haematuria and recurrent urinary tract infections (UTIs). He has been performing intermittent self catheterisation (ISC) for detrusor underactivity for over 20 years. A flexible cystoscopy showed these appearances of...

Post-orgasmic illness syndrome

Introduction Disorders of ejaculation are a rare and poorly understood subsection of male sexual dysfunction. A paucity of evidence has hindered advances in definitions, epidemiology, pathophysiology and management. The licensing of a specific medication for premature ejaculation signalled the research...