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Kidney stones in pregnancy
Urolithiasis related complications are estimated to affect between 1:200 and 1:2000 pregnancies [1,2]. With around 825,000 conceptions in England and Wales in 2021 [3], this represents an uncommon but not rare occurrence. What is normally a straightforward pathway for a...Clear cell urothelial carcinoma: a highly aggressive morphological variant in the bladder and upper urinary tract
Clear cell urothelial carcinoma (CCUC) is a rare morphological variant of transitional cell carcinoma (TCC). It can occur anywhere along the urothelial tract and is characterised histologically by high grade carcinoma with an abundance of clear, glycogen-rich cytoplasm [1]. Alternative...Medical journal readers
Keeping up to date with a variety of urology and medical journals can be an onerous task. Each year there is an ever-expanding number of medical journals and finding a way to sift through relevant information in medical journals and...
RN or PN for small RCCs – the debate continues
This is a retrospective study to evaluate kidney function and overall survival (OS) in patients who underwent partial nephrectomy (PN) and radical nephrectomy (RN) for RCCs <4cm. They looked at 2110 patients who underwent RN/PN for T1a renal cell carcinomas...Prostate cancer survivorship: a new path for uro-oncology
Over two million people in England have a diagnosis of cancer [1]. Of this figure, over 250,000 have been diagnosed with prostate cancer [2]. However, during the next decade, a rapid increase in the number of new cancer diagnoses, as...Lasers in urology
1. What does LASER stand for? 2. What elements are involved and how is a LASER created? 3. The following cases involve laser surgery. Can you diagnose the pathology, identify which type of lasers can be used, and their wavelengths?...
Are standard repeat biopsies during active surveillance for prostate cancer still necessary?
Active surveillance (AS) has emerged as a key strategy for managing low-risk prostate cancer (PCa), offering an alternative to immediate treatment. Initially, AS relied on prostate specific antigen (PSA) testing, digital rectal examinations (DRE), and systematic biopsies. Early studies using...
PSA screening in limbo: how low should we go?
One may wonder how the management of prostate cancer could have evolved differently if it had followed a path similar to breast cancer. In breast cancer, early detection in the 1970s relied heavily on imaging because no reliable circulating biomarker...
