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Retention after Botox therapy in OAB
Treatment of overactive bladder (OAB) has a wide spectrum. The first step is lifestyle modifications, the second step is pharmacotherapy and the third line is intradetrusor injections with Botox®. This retrospective study is from Tennessee, USA in non-neurogenic and refractory...
Intermittent self-catheterisation
Intermittent self-catheterisation (ISC) is used in everyday practice for bladder dysfunction. This study from Southampton, UK presents a Cochrane review of different catheter designs, user satisfaction and incidence of urinary tract infection (UTI), etc. The following factors were looked at:...
Testosterone and erectile function – the debate goes on!
The most common causes of erectile dysfunction (ED) as per European Association of Urology (EAU) guidelines are: psychogenic, vasculogenic, neurogenic and hormonal. The EAU 2017 guidelines recommend measuring total testosterone (TS) level. This study is a meta-analysis of 14 randomised...
Bladder cancer outcomes in patients with spina bifida
These authors carried out a systematic review using PubMed and a number of terms to pick up studies with an underlying diagnosis of myelomeningocele and bladder cancer, with exclusions of cord injury, tuberculosis, schistosomiasis, or prior ureterosigmoidostomy. Their aim was...
Hypospadias surgery complication rates
These authors identified all children undergoing NHS hypospadias surgery between 1999 and 2009 in England using the hospital episode statistic database and looked at repair types and complications. High-volume centres (24/75) were classified as such if they did more than...
RARP – novel uroflow stop test
More and more centres are doing robotic assisted radical prostatectomy (RARP) surgery for cancer of the prostate .This study from Montreal, Canada describes a simple and novel test to predict recovery of urinary continence after RARP. The uroflow stop test...
IC and risk of CHD
Bladder pain syndrome / interstitial cystitis (BPS/IC) is a chronic, multifactorial and relapsing condition. Aetiology includes: inflammation, allergic, neuropathic, auto immune, vascular factors, etc. This study from Taiwan aimed to investigate the risk of coronary heart disease (CHD) among IC...
Antibiotics and flexible cystoscopy
This study is from Memorial Sloan-Kettering Hospital in New York, USA. Thousands of flexible cystoscopies are performed every day worldwide. Do they need antibiotic cover? Flexible cystoscopy may cause urinary tract infection (UTI) in less than 10% of cases. Asymptomatic...
Reflux oesophagitis and risk of interstitial cystitis: is there a link?
This study aims to explore the potential link between reflux oesophagitis (RE) and interstitial cystitis / bladder pain syndrome (IC/BPS). IC/BPS is a chronic disease which is difficult to diagnose and treat. Two percent of the population may be affected....
Incidence and risk factors of suicide after a prostate cancer diagnosis
This is an observational study looking at 1,281,393 men diagnosed with prostate cancer and 842,294 matched prostate cancer-free men. There was an overall increased relative risk of suicide of 2.01 in men diagnosed with prostate cancer compared to those without,...
Post prostatectomy outcomes of patients with high-risk prostate cancer treated with neoadjuvant androgen blockade
This is an interesting paper reporting on the use of neoadjuvant androgen blockage in patients with high-risk prostate cancer undergoing radical prostatectomy. Previous work in the literature has shown an improvement in the rate of organ-confined disease and decreased positive...
