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New therapy for overactive bladder
Overactive bladder (OAB) is a complex symptom that can adversely affect quality of life. So far pharmacotherapy has focused on anti-cholinergic drugs. Recently, beta-adrenoreceptors have been identified as having an effect on the detrusor muscle and urothelium. Beta-3 is the...Penile cancer: a practical approach
Penile cancer is rare and accounts for less than 1% of all new cancer cases in males in the UK, with around 640 new cases diagnosed every year [1]. In England and Wales, the annual incidence is between 1.2 and...EBM Stats Calc: there’s a stat for that
Quantifying the value of a specific test or intervention for a patient is no easy feat. Even when the value of a given test or intervention has been established, there may be additional case-specific factors to consider that are not...Focal therapy for prostate cancer – ready for prime time?
The current therapeutic ratio for radical therapy in many men with localised prostate cancer is not ideal. For a significant side-effect profile, there seems to be a small survival benefit over a 10-15 year period. A strategy that might balance...
Reliability of grading of VUR and other findings on VCUG
The gold standard for diagnosing VUR is still the voiding cycstogram (VCUG). These authors looked at the inter observer variability of grading of vesicoureteral reflux (VUR) using a VCUG and highlight the implications for treatment and prognosis as a results....
Outcomes of renal cancer surgery on renal function and mortality on those with and without CKD
In urology we are encountering an ageing and more comorbid population, including a group of patients with chronic kidney disease (CKD). In this retrospective study, a group from the Cleveland Clinic present the extended follow-up of patients with and without...
Long-term complications of bulking agents in the treatment of SUI
Incontinence poses a substantial economic burden on the UK’s NHS, estimated at £536 million in 1999/2000, equivalent to approximately 1.1% of the total NHS spend, for both men and women. Over two decades later, this cost is expected to have...
