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Basic Urological Sciences

The scientific foundation of any discipline is, as the name suggests, basic to the understanding of pathophysiology, mechanisms, physiologic and pharmacologic interactions, and technology. It arms the clinician with the ability to challenge dogma and keep pace with recent advances...

Reliability of grading of VUR and other findings on VCUG

The gold standard for diagnosing VUR is still the voiding cycstogram (VCUG). These authors looked at the inter observer variability of grading of vesicoureteral reflux (VUR) using a VCUG and highlight the implications for treatment and prognosis as a results....

Radium-223 treatment outcomes after multiple lines of mCRPC therapy in clinical practice: implication of pre-treatment spinal epidural disease

There are a number of treatments now available to patients with metastatic castrate-resistant prostate cancer (mCRPC). However, the optimal timing and order in which they are given is less clear. Radium-223 was FDA-approved for mCRPC patients with symptomatic bone metastases...

Research needs you

This was an eye-catching front cover headline for the BMJ. Is research as important as clinical duties? The answer has to be yes. Research takes place in every NHS hospital, albeit in a fragmented way. All of us have to...

Retention after Botox therapy in OAB

Treatment of overactive bladder (OAB) has a wide spectrum. The first step is lifestyle modifications, the second step is pharmacotherapy and the third line is intradetrusor injections with Botox®. This retrospective study is from Tennessee, USA in non-neurogenic and refractory...

Developing and validating a new nomogram for diagnosing BOO in women

Bladder outlet obstruction (BOO) in women is thought to be present in between 2.7% and 27%. Causes of BOO in women may be anatomical or functional. Yet, unlike the diagnosis in men, there is no standard definition for BOO in...

Standard versus expanded cultures to diagnose UTIs in women

Clinicians are well aware of the limitations of the so-called Kass criteria applied to standard urine culture (SUC) techniques as well as the limitations of empiric antibiotic prescribing for symptoms that are known to overlap with chronic conditions such as...

Surgical video – part 2: Tips on how to edit and create a finished surgical video for teaching or publication

A well-made and informative video can be one of the most valuable promotional tools for a department of urology. Having to resort to an external commercial source to produce a video can be prohibitively expensive. With the extensive computing power...

What is the role of evidence-based medicine in urology?

The concept of ‘evidence-based medicine’ (EBM) was first developed in the early 1990s and was described as “the conscientious, explicit and judicious use of the current best evidence in making decisions about the care of individual patients” by the recently...

An introduction to research governance

Research is the process of acquiring new generalisable knowledge and should be fully integrated into healthcare work. There is a growing drive to encourage and further develop evidence-based practice in medicine so that staff and patients benefit from improved healthcare...

Should it be a mandatory requirement for medical students to receive the COVID-19 vaccine to attend clinical attachments?

The vast majority of medical students have positive attitudes towards the COVID-19 vaccine for themselves and patients, however, what about the small inevitable minority who resist it? Should they be prevented from attending clinical attachments in the NHS? It is...

New drug hope for prostate cancer patients

• Hormone therapy is used to slow the progression of advanced prostate cancer, but cancers often develop resistance and continue to grow.• Research reveals that patients with higher levels of heat shock proteins have worse outcomes.• Targeting these proteins with...