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An introduction to research governance

Research is the process of acquiring new generalisable knowledge and should be fully integrated into healthcare work. There is a growing drive to encourage and further develop evidence-based practice in medicine so that staff and patients benefit from improved healthcare...

Should it be a mandatory requirement for medical students to receive the COVID-19 vaccine to attend clinical attachments?

The vast majority of medical students have positive attitudes towards the COVID-19 vaccine for themselves and patients, however, what about the small inevitable minority who resist it? Should they be prevented from attending clinical attachments in the NHS? It is...

medac Pharma launch education platform, medac Academy

medac Pharma have launched a new digital education platform for UK healthcare professionals, medac Academy.

Intravesical GAG replacement therapies for bladder pain syndrome / interstitial cystitis – an update

The barrier function of the glycosaminoglycan (GAG) layer of the urothelium was identified by Parsons in 1975, and intravesical therapies to treat chronic inflammatory conditions of the bladder were developed soon after. However, the active role of the urothelium in...

Selective denervation of the bladder

The treatment of refractory overactive bladder is currently limited to neuromodulation (sacral nerve stimulation or percutaneous tibial nerve stimulation) or botulinum toxin injections. Although all these options are valuable, they have their own limitations and may not be suitable for...

Model to predict malignancy among Bosniak III cysts

This retrospective study over a 15-year period is to identify independent predictors of malignancy in Bosniak III (BIII) renal lesions and to build a prediction model based on identifiable clinical variables. These cysts, characterised by contrast-enhanced computed tomography (CECT), have...

Urodynamics in review: stress urinary incontinence in women produced by the Urodynamics Committee of the ICS

Urodynamic studies (UDS) are the best tools to objectively assess the lower urinary tract dysfunction (LUTD) of various aetiologies [1]. According to the general understanding and consensus of the medical community UDS should be performed only when they will change...

Prostate Cancer: Clinical Case Scenarios

This is a useful book to browse through, particularly for trainees. There are 195 pages of clinical information divided into 13 chapters. It’s a slim book which is easy to pick up and read. It uses case scenarios to discuss...

CROWN initiative – what is it about?

The editors of around 50 journals related to women’s health have joined forces to support the CROWN initiative (core outcomes in women’s health). The aim is to standardise the collection of outcomes for all trials in a specific dataset in...

Update on urodynamic equipment performance

This article is from the steering committee of the International Continence Society (ICS) and it gives a comprehensive account of what is required from modern urodynamic machines. It will be of interest to purchasers, designers and clinical users (doctors and...

NICE - what we need to know?

The National institute for Health and Care Excellence (NICE) reached 17 years old in April 2016. As clinicians, we are reading and discussing NICE guidelines on a daily basis in multidisciplinary team meetings. NICE is always in the news, whether...

Femeda commence innovative real world clinical trial for Pelviva

A major 330 patient randomised ‘real world’ clinical trial has commenced for Pelviva in conjunction with the University of Manchester and South Manchester GP federation. The trial will compare Pelviva against...