You searched for "MET"
Abiraterone acetate in men with castration-resistant prostate cancer
With emerging results from the Stampede and Latitude studies, abiraterone has taken the forefront in the management of metastatic prostate cancer while researchers try to identify the ideal timing for administration. It is a potent inhibitor of CYP17 which results...
Understanding gender differences in nephrolithiasis
Rates of nephrolithiasis are higher in males than females. The cause for this remains unclear, however animal models have demonstrated an association between sex steroid hormone levels and lithogenesis. This relationship in humans is less well established. This study from...
Liquid paraffin versus lidocaine
Topical anaesthetics have been used in urology since 1884, when Pease described using “cocaine in a sensitive urethra with charming results”. Since 1949, 2% lidocaine has been increasingly used intraurethrally for cystoscopy and other procedures. This article is a pilot...
Penile clamp device – a new indication?
This study originates from New Zealand and looks at men affected by post-prostatectomy incontinence (PPI). These patients are difficult to manage with the options of further surgery, indwelling catheters or pads. The aim of this questionnaire study (IIQ 7) was...
The natural history of prostate cancer on MRI
Multiparametric MRI features heavily on a number of active surveillance protocols. This study looked at 86 men on active surveillance who had an mpMRI prior to 2013 to assess how lesions changed over time. Two blinded radiologists examined all the...New £1.9M drug trial could delay relapse for prostate cancer patients
A new drug could keep cancer under control for longer for men with advanced prostate cancer and will be tested in a new trial funded with £1.9 million from Prostate Cancer UK. Current treatments, like chemotherapy or hormone-targeting therapies, can...Demanding cases or nightmares in uro-oncology? Sep/Oct 2022
Treatment of prostate cancer in renal transplant recipients is challenging due to a lack of knowledge of the natural history of cancer in these patients, the anatomical position of the graft in the iliac fossa and its proximity to the...The final hurdle: the consultant interview
The consultant interview is undoubtedly the most important exam you’ll ever sit; but curiously even the best and most motivated trainee becomes somewhat fatalistic when approaching this, the most important of all hurdles. Gone are the days when deals were...Bladder cancer: the common cancer many people still miss
For Bladder Cancer Awareness Month this May, leading charity Action Bladder Cancer UK is highlighting one of the most commonly overlooked warning signs of bladder cancer – blood in the urine. Bladder cancer is one of the most common cancers...An overview of non-surgical treatment options for Peyronie’s disease
Peyronie’s disease (PD) is a therapeutic challenge despite the availability of several non-surgical and surgical options. Very few of these options are supported by good quality evidence according to the current American and European guidelines [1-3]. The period of plaque...
