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393 results found

Abiraterone acetate in men with castration-resistant prostate cancer

With emerging results from the Stampede and Latitude studies, abiraterone has taken the forefront in the management of metastatic prostate cancer while researchers try to identify the ideal timing for administration. It is a potent inhibitor of CYP17 which results...

Predictors of vaginal mesh exposure after mid-urethral sling placement

Vaginal mesh exposure following mid-urethral sling (MUS) insertion can be a difficult complication to treat. The aim of this study was to identify possible risk factors in patients who had unfortunately developed vaginal mesh exposure following MUS surgery. This was...

PET imaging of prostate-specific membrane antigen in prostate cancer

Molecular imaging utilising prostate-specific membrane antigen (PSMA) as a target has increasingly been mentioned at key conferences and meetings. PSMA is a membrane metalloenzyme that is overexpressed in prostate cancer, with the degree of expression appears to correlate with tumour...

Should maximal urethral closure pressure be performed before mid-urethral sling surgery for stress incontinence?

Maximum urethral closure pressure (MUCP) is a means of trying to provide an objective assessment of urethral integrity. In some centres it is used as a tool to help predict outcomes after mid-urethral sling (MUS) placement. The authors propose that...

Retention after Botox therapy in OAB

Treatment of overactive bladder (OAB) has a wide spectrum. The first step is lifestyle modifications, the second step is pharmacotherapy and the third line is intradetrusor injections with Botox®. This retrospective study is from Tennessee, USA in non-neurogenic and refractory...

MDT meetings in urogynaecology

This study aimed to assess the outcome of case discussion at a single unit’s urogynaecology multidisciplinary team (MDT) meetings. This was a retrospective study of the MDT proformas of 106 patients who were discussed over a 14-month period. Various outcomes...

Prostate cancer detection rate of MRI-TRUS fusion vs. systematic biopsy

With the advent of one-stop prostate cancer diagnostic clinics, the findings of this study are of interest to readers who may be considering introducing the technique of magnetic resonance imaging transrectal ultrasound (MRI-TRUS) fusion biopsies to their practice. A retrospective...

UTI and VUR in children with mild antenatal hydronephrosis

This paper describes a retrospective analysis of 760 (608 males, 162 females) patients identified with mild antenatal hydronephrosis (defined by an anteroposterior (AP) pelvic diameter of 7-10mm in the third trimester and persistent postnatal dilation) looking at the incidence of...

Impact of internal spermatic artery preservation during laparoscopic varicocelectomy

There is still considerable controversy about the optimal surgical treatment of adolescent varicocele. One of the dilemmas is whether or not to preserve the internal spermatic artery (ISA) when carrying out a laparoscopic Palomo procedure. This paper looks at retrospective...

Long-term bladder drainage: blessing or disaster in disguise

Chronic bladder dysfunction occurs in many neurologic disorders e.g. multiple sclerosis, Parkinson’s disease, stroke, etc. Suprapubic catheters (SPC) are inserted every day and every urology department has a pool of ‘difficult’ patients who keep coming back. This paper compares SPCs...

Dilemma of second primary tumour

Long-term survival in localised prostate cancer (CaP) can be achieved with treatment by either radical prostatectomy (RP) or external beam radiotherapy (EBRT). The development of second primary tumour is poorly understood in such cases. This retrospective study included 84,397 cases...

Convective radiofrequency water vapour thermal therapy for BPH

There are a number of new treatments for benign prostatic hyperplasia (BPH) on the market. This paper reports retrospective data for 129 patients treated with convective radiofrequency water vapour thermal therapy (Rezum) by a single surgeon. There is variable length...