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Intravesical GAG replacement therapies for bladder pain syndrome / interstitial cystitis – an update
The barrier function of the glycosaminoglycan (GAG) layer of the urothelium was identified by Parsons in 1975, and intravesical therapies to treat chronic inflammatory conditions of the bladder were developed soon after. However, the active role of the urothelium in...Intravesical glycosaminoglycan analogue instillations for recurrent cystitis
Introduction The symptoms of recurrent cystitis can be triggered by inflammatory or infective causes. Bladder pain syndrome (BPS) and bacterial recurrent lower urinary tract infection can both present with symptoms of recurrent cystitis and cause significant morbidity in affected individuals....Stone Pass: Kidney Stones app
For this Digital Review I have focused on the Stone Pass: Kidney Stones app (Know Stone LLC) – a new information tool for patients with ureteric stones. I had recently seen a shared tweet originating from the app’s author Dr...Demanding cases or nightmares in endourology? Nov/Dec 2017
Case 1 A 78-year-old male was transferred from a referring hospital. He had a cystectomy and ileal conduit performed 15 years previously and had recently been admitted with a clinical diagnosis of an infected obstructed kidney. The referring hospital had...What is new in lasers for endourology: looking into the future
From the first cystoscopic argon and neodymium-YAG (yttrium-aluminium-garnet) laser used for bladder tumours in 1976 by Staehler et al. [1], lasers have proven to be a versatile and an evolving tool in the therapeutic management of a variety of urological...Modern management of small renal masses
With the advent of widespread cross-sectional imaging there has been a surge in incidental detection of small renal masses (SRMs) and renal cell carcinoma (RCC) is now the seventh most common cancer in the UK. Whilst surgical excision for larger...Assessment and management of percutaneous nephrostomies
Nephrostomies are a valuable uroradiological intervention which enables drainage of the obstructed kidney, amongst other indications. Complications associated with nephrostomies following placement are not uncommon, with re-presentation to the emergency department or surgical emergency unit. In this review we will...
PUJO: Hellstrom principle revisited
This paper describes the result of four out of twenty-three cases (two males, two females) of pelvi-ureteric junction obstruction - PUJO - (mean age 18.25 years, range 16-20), mean follow-up two years (range six months – three years) that were...
Prostatic calculi and CIC
Although the clinical importance of prostate calculi has been debatable, it is a disease that can cause a plethora of symptoms and signs – sometimes in disguise. Clean intermittent catheter (CIC) is the gold standard method for bladder rehabilitation /...
Sacral agenesis and neurogenic bladder: long-term outcomes of bladder and kidney function
These authors looked at single institution outcomes for sacral agenesis (without spina bifida) with reference to renal function and bladder function. All had urodynamics either at diagnosis (56%) or soon after. Of 43 patients (23 female, 20 male), 37 had...
Stepwise voltage ramping causes less renal haematomas than fixed maximal voltage ESWL
Extracorporeal shock wave lithotripsy (ESWL) remains the recommended first line treatment for stones <2cm in the renal pelvis and upper or mid-pole calyces (Türk C, Knoll T, Petrik A, et al. European Association of Urology Guidelines on Urolithiasis. 2014). There...
