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Recent advances in the management of castration resistant prostate cancer

1 November 2017 | | URO - Urologic Oncology
Castrate resistant prostate cancer (CRPC) is defined by disease progression despite androgen-deprivation therapy lowering testosterone to castrate levels. It may present as a rise in serum levels of prostate specific antigen (PSA), progression of pre-existing disease, or the appearance of...
BMJ cover with Editor's Choice stamp

Beware of the ambiguous testicular lump

1 September 2019 | | URO - Functional / Reconstructive Urology, URO - Infection, URO - Trauma & Emergency, URO - Urologic Oncology
In busy day-to-day practice, we are often faced with puzzling situations. A useful mnemonic is 4-T: torsion, trauma, tumour and tuberculosis (infections). This case review in the BMJ is about a 34-year-old man presenting to A&E with left testicular pain...

The NICE Guideline on Urinary Incontinence: the management of urinary incontinence in women

1 May 2014 | | URO - Functional / Reconstructive Urology
Background Urinary incontinence (UI) is a common symptom that can affect women of all ages. It is difficult to estimate the prevalence of UI since it is often under-reported, although the Norwegian EPINCONT study looking at women over 20 reported...

Bladder urothelial neoplasms in children

1 January 2016 | | URO - Paediatric Urology
Urothelial bladder neoplasms are rare in children, occurring in 0.1-0.4% of the population before the age of 20. There are no current paediatric guidelines to their management. This study retrospectively reviews the files of patients from three tertiary centres between...

Demanding cases or nightmares in uro-oncology? Jan/Feb 2022

5 January 2022 | | URO - Urologic Oncology
When less is more: percutaneous biopsy and tumour seeding in papillary renal cell carcinoma Renal cell carcinoma (RCC) accounted for 2.2% of new cancer diagnoses worldwide in 2018 with over 400,000 new cases and 175,098 deaths [1]. The majority of...

Urinary retention in women: what a general urologist should know

6 November 2024 | | URO - Functional / Reconstructive Urology
Urinary retention (UR) is classified by the International Continence Society (ICS) into acute (AUR) and chronic (CUR). AUR is defined as the “inability to pass any urine despite having a full bladder which is painfully distended and readily palpable or...

COVID-19: the impact on a junior registrar

26 May 2020 | | URO - Covid-19
Prior to the coronavirus pandemic I was a trust grade junior registrar, using this year at a district general hospital to gain experience, skills and portfolio points for round two of National Selection. My urology registrar on-call duties would consist...

Post radical nephrectomy presenting with skull metastasis

10 April 2024 | | URO - Urologic Oncology
We present the case of an 83-year-old female who underwent right radical nephrectomy for renal cell carcinoma (RCC). Despite negative surgical margins, the patient presented with a skull metastasis six years post radical nephrectomy. This case highlights the importance of...

Demanding cases or nightmares in uro-oncology? May/Jun 2022

3 May 2022 | | URO - Urologic Oncology
Delayed diagnosis of testicular cancer Testicular cancer is considered rare in the general population but is the most common cancer affecting males between 24 and 49 years. The diagnosis of testicular cancer depends on physical examination, ultrasound findings and tumour...

Understanding Stauffer’s syndrome

1 May 2018 | | URO - Andrology, URO - Basic Science Research, URO - Endourology & Stones, URO - Functional / Reconstructive Urology, URO - Infection, URO - Neurourology, URO - Paediatric Urology, URO - Technology, URO - Trauma & Emergency, URO - Urologic Oncology, URO - Uroradiology
Who was Stauffer and what is Stauffer’s syndrome? Maurice Stauffer (1915-1994) was a gastroenterologist at the Mayo Clinic in Rochester, United States, and in 1961 first characterised the non-metastatic, paraneoplastic effects of renal cell carcinoma (RCC) on liver size and...

Keeping your eye on the ball: atypical presentations of testicular malignancy

4 March 2025 | | URO - Urologic Oncology
Most testicular cancers present with a painless lump on the testes, and most are confidently diagnosed on examination and ultrasound. They have an excellent prognosis, with 90% patients alive at 10 years [1]. However, advanced testicular cancer, or those with...

Delivering a laparoscopic urology workshop in West Africa: our initial experience in Senegal

4 September 2020 | | URO - Endourology & Stones, URO - Technology
Despite universal adoption and significant technological innovation since its inception around 30 years ago, access to laparoscopic surgery remains lacking in Sub-Saharan Africa (SSA). Whilst some progress has been made in recent years to bridge the gap with the developed...