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Predictive factors for conservative treatment failure in paediatric blunt renal trauma

1 March 2017 | | Paediatric Urology, Trauma and Emergency Urology | Complications, Kidney, Pediatrics, Treatment outcome, Wounds and injuries
Blunt renal trauma is managed conservatively in children in the vast majority of cases. Grade IV renal injury is also generally managed non-operatively although occasionally intervention is needed for a urinoma that fails to settle. These authors retrospectively looked at...

Comparing intravesical chemohyperthermia with Mitomycin C versus BCG in treating bladder cancer

1 July 2016 | | Urologic Oncology | BCG, Device-assisted therapy, Hyperthermia, Intravesical chemotherapy, Mitomycin-C, Non–muscle-invasive bladder cancer, Radiofrequency, Randomised controlled trial, Recurrence rate, Thermochemotherapy
In the advent of the recent Bacillus Calmette–Guérin (BCG) crisis, the importance of alternative adjuvant treatments for intermediate- and high-risk non-muscle-invasive bladder cancer (NMIBC) has been highlighted. Chemohyperthermia (CHT) has emerged as an option, however there remains a lack of...

BCG maintenance therapy not superior to induction alone

1 July 2015 | | Urologic Oncology | Bacillus Calmette-Guérin, Bladder cancer, Maintenance therapy
With the ongoing shortage of BCG remaining an issue for urologists in the UK and further afield, this topical paper presented the results of the CUETO study evaluating the outcome of a modified three-year BCG maintenance regimen versus induction therapy...

BCG strain differences have an impact on clinical outcome in bladder cancer immunotherapy

1 March 2015 | | Urologic Oncology | Animal, BCG Connaught, BCG Tice, BCG vaccine, Flow cytometry, Immunotherapy, Intravesical drug administration, Models, Randomized controlled trial, Urinary bladder neoplasms
Bacillus Calmette-Guérin (BCG) has been part of the treatment algorithm for non-muscle invasive bladder cancer (NMIBC) for a number of years. In this single centre, prospective, randomised trial, two of the most commonly available strains, BCG Connaught and BCG Tice,...

Prevention of urethral stricture recurrence

1 September 2014 | | Functional Urology
Urethral stricture recurrence after urethral reconstruction is one of the most challenging problems in urology. With the increase in endoscopic surgery over the last three decades the incidence of urethral strictures has increased, with iatrogenic manipulation the leading aetiology in...

Comparison of PCNL under spinal versus general anaesthesia

1 May 2014 | | Endourology and Stones
There are several advantages of performing percutaneous nephrolithotomy (PCNL) under spinal anaesthesia including lower cost, reduced adverse effects and less tracheal tube displacement. Another advantage is that the patient remains awake throughout making positioning easier and reducing the risk of...

Prilocaine irrigation for pain relief after TURP

1 March 2014 | | Endourology and Stones
Transurethral resection of the prostate (TURP) is one of the commonest procedures undertaken by urologists. There are well known complications following the procedure which commonly include haematuria but also TUR syndrome, failure to pass urine and infections, amongst others. The...

A phase II dose-ranging study of mirabegron in patients with OAB

1 March 2014 | | Functional Urology
This was a multinational, multicentre, randomised, double–blind, double-dummy, parallel group placebo- and active- controlled phase II study. The study enrolled 1108 men and women aged 18 and over. The criteria were: patients must have had overactive blader (OAB) symptoms for...

Early complications following ambulatory hypospadias repair

5 November 2019 | | Paediatric Urology, Reconstructive Urology | Complications, Hypospadias repair, Readmission, Reoperation
Most hypospadias repairs are undertaken on a day case ambulatory basis. Roth et al. have studied clinically significant events occurring within 30 days of operation. Data was obtained from the Paediatric Health Information System (PHIS), an administrative database that contains...

So you want to go on a fellowship – part II: the research year

1 November 2016 |
This article is the second in a three-part series which follows directly on from the first part which concentrated on the rationale for going on a fellowship, as well as some of the administrative hurdles you might face in planning...

ICS 2019: 49th Annual Meeting of the International Continence Society

3 September 2019 -6 September 2019 | Functional Urology, Basic Science Research
For 2019, Sweden’s second city, Gothenburg, welcomes the Annual Scientific Meeting of the International Continence Society. Not since 1981, when Lund was the host, has Sweden hosted the ICS and the local organising committee are working hard to ensure that...

A guide to percutaneous nephrolithotomy

1 July 2019 | | Endourology and Stones
Percutaneous nephrolithotomy (PCNL) is now the gold standard approach to treating large renal stones. Since its development in the 1970s, it has undergone a series of refinements that could only have been possible with the symbiosis of both radiological and...