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Outcomes of renal cancer surgery on renal function and mortality on those with and without CKD

In urology we are encountering an ageing and more comorbid population, including a group of patients with chronic kidney disease (CKD). In this retrospective study, a group from the Cleveland Clinic present the extended follow-up of patients with and without...

Testicular cancer: management of stage I seminoma

Introduction Testicular cancer is the most frequently occurring solid tumour in men between the ages of 15 and 34 years [1]. About 60% of cases are seminomas and approximately 70-80% of them have, at presentation, clinical stage I disease. This...

Priapism in sickle cell disease

What is sickle cell disease? Sickle cell disease (SCD) is one of the most common single-gene disorders in the UK affecting approximately one in every 2000 live births. Approximately 20-25 million people worldwide have SCD. It predominately affects those of...

Penn Clinical Manual of Urology

This is a powerhouse of a textbook. Small enough to fit into a modest briefcase (but not quite small enough to fit into the pocket of a white coat – for those who remember them) it punches well above its...

The PROMIS trial – time for multi-parametric MRI before a first prostate biopsy

Whilst the relatively random process of 12 core transrectal ultrasound guided (TRUS) prostate biopsy remains by far the most widely employed approach to prostate cancer diagnosis in the UK, its flaws as a standalone diagnostic strategy are increasingly apparent. TRUS-biopsy...

Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer

Abiraterone acetate, the prodrug of abiraterone, blocks endogenous androgen synthesis by inhibiting cytochrome p-450c17, a critical enzyme in androgen biosynthesis. Its active D4A metabolite also has anti-tumour effects through possibly multiple mechanisms. 3-5% of men diagnosed with prostate cancer in...

Bladder Health UK

- CHARITY FOCUS - Bladder Health UK is a national patient support charity that has been communicating with bladder illness sufferers for 30 years. The charity offers a lot of resources to give help, educate and inform, including webinars, study...

Prodromal period of Fournier’s gangrene

Necrotising soft tissue infections of the genitalia (NSTIG), commonly known as Fournier’s gangrene, is a rare but important surgical emergency associated with significant morbidity and mortality. It is estimated that every six hours of delay in surgical debridement leads to...

Geoffrey Parker (1902-1973) – urologist to the French Resistance!

In this series of articles I am going to show you some of the exhibits contained in the Museum of Urology, hosted on the BAUS website (www.baus.org.uk). This time, I am joined by Jasmine Winyard, urology trainee in Leicester; we...

Clean catch urine from babies – the ‘quick wee method’

Urinary tract infections (UTIs) are common in children and babies and can lead to urosepsis, renal scarring and chronic kidney disease. As per American Academy of Pediatrics guidelines, urine samples are a must in febrile / unwell infants even if...

Fournier’s gangrene

Introduction Fournier’s gangrene (FG) is a rare but fulminant form of infective necrotising fasciitis affecting the perineum and external genitalia, which can rapidly progress along fascial planes. It most commonly affects men, but can occur in women and children, with...

Adrenal incidentalomas: what next?

An incidentaloma refers to an adrenal lesion >1cm discovered incidentally during radiologic examination. Identifying a malignant and / or functioning lesion is critical for management. However, as the majority of lesions are benign, the challenge is the identification of malignant...