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PSM increases risk of recurrence after PN for high-risk renal tumours

Positive surgical margins (PSM) for solid organ malignancies are associated with adverse oncological outcomes. However, for RCC the prognostic significance of PSM after partial nephrectomies (PN) remains a matter of debate. As PN is more increasingly being used to excise...

Pre-transplant management of valve bladder

This paper examines the evidence concerning the timing, indications and problems associated with augmentation cystoplasty (AC), posterior urethral valves (PUV), and end stage renal failure (ESRF) using a literature review via Medline, Cochrane library and LILACS databases. Two search strategies...

Radiation exposure – what is the optimal imaging modality in the follow-up of patients with urinary tract calculi?

Cumulative radiation dose is an important consideration in the nephrolithiasis patient population. Exposure to ionising radiation is known to be harmful and is associated with an increased risk of malignancy. Understanding radiation doses is necessary to make informed decisions regarding...

Cardiac failure and medical therapy for LUTS / BPH

Alpha blockers (AB), 5-alpha reductase inhibitors (5-ARI) and combination therapy are widely prescribed for lower urinary tract symptoms (LUTS) considered consequent to prostatic enlargement and are the mainstay of first-line therapy. This retrospective interrogation of a large population-based dataset of...

Importance of PSA variation – an analysis of PLCO trial data

This study looks specifically at the group of patients in the intervention arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening trial (PLCO), to investigate variations in prostate specific antigen (PSA) level. They have specifically included only patients who...

Urethral pain syndrome – is there a light at the end of the tunnel?

Urethral pain syndrome (UPS) is defined in the 2014 EAU Guidelines as the occurrence of chronic or recurrent episodic pain perceived in the urethra, in the absence of proven infection or other obvious local pathology. UPS is often associated with...

Predicting bone scan positivity in non-metastatic CRPC

There is evidence that suggests that early treatment with chemotherapy, immunotherapy or hormone therapy leads to a better response in patients with asymptomatic metastatic castrate resistant prostate cancer (CRPC). This study aimed to predict bone scan positivity in patients with...

Is surgical antibiotic prophylaxis necessary for paediatric orchiopexy?

With the rise of resistant organisms to most commonly used antibiotics, there is a plea for judicious use of antibiotics, especially for clean surgical procedures. Potential adverse events associated with antibiotic use include allergic reaction (including anaphylaxis), clostridium difficile infection,...

Testicular prostheses satisfaction

This is a satisfaction survey in 40 patients who had underwent radical orchidectomy and had saline filled testicular prosthesis (TP) over a 3 year period in US, as the silicone implants are not in use since 1995 in US. No...

Prodromal period of Fournier’s gangrene

Necrotising soft tissue infections of the genitalia (NSTIG), commonly known as Fournier’s gangrene, is a rare but important surgical emergency associated with significant morbidity and mortality. It is estimated that every six hours of delay in surgical debridement leads to...