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Demanding cases or nightmares in uro-oncology? Sep/Oct 2021

3 September 2021 | | Urologic Oncology
Active surveillance for prostate cancer: missing the boat Case In 2005 a 43-year-old man of Afro-Caribbean ethnicity was referred to our centre for investigation of suspected prostate cancer. Digital rectal exam revealed a firm right lobe, PSA of 2.3ng/ml, prostate...

The role of transperineal template biopsies in the diagnosis of prostate cancer

1 March 2014 | | Urologic Oncology
The case In 2002, Mr A, a 64-year-old software engineer, was referred by his GP for further investigation of a raised prostate specific antigen (PSA) of 6.2. His prostate felt benign. He underwent transrectal ultrasound guided (TRUS) prostate biopsies. This...

Urological Cancer Management

1 May 2018 | | Urologic Oncology
This was all in all a pretty good read. It covers a wide range of topics authoritatively and with a degree of confidence that allows for quite a focused discussion on a range of malignancies from adrenal glands to penile...

Is TRUS and biopsy obsolete as a diagnostic test for prostate cancer: refining the perineal biopsy technique?

1 March 2015 | | Urologic Oncology | active surveillance, biopsy, Complications, prostate cancer, staging, transperineal biopsy
Whilst there has been a dramatic shift in how patients are investigated for potential prostate cancer, transrectal ultrasound (TRUS) and biopsy remains the most commonly used technique for tissue sampling. In this single centre, retrospective analysis, 634 men, over a...

Use of MRI in the evaluation of prostate cancer: part 1

1 January 2015 | | Urologic Oncology, Uroradiology
Introduction Prostate cancer remains the most commonly diagnosed cancer in males and the second leading cause of cancer related deaths in UK men, after lung cancer [1]. The incidence of prostate cancer in the UK has shown a rapid increase...

Cryotherapy in prostate cancer

1 March 2015 | | Urologic Oncology | Cryotherapy, cryosurgery, cryoablation, subtotal cryotherapy, targeted focal therapy, prostate cancer, prostate
This review of the literature aims to summarise what is known in regards to outcomes in patients undergoing cryotherapy in a number of settings: whole gland, salvage and targeted focal therapy. It highlights that more prostate cancers are being diagnosed...

Focal therapy trials

6 November 2020 | | Urologic Oncology
Men with localised prostate cancer have traditionally required whole gland treatment involving radical prostatectomy or radical radiation treatment, independent of disease location and size. Increasing evidence supports the use of active treatment only in those men diagnosed with prostate cancer...

Priapism in sickle cell disease

2 March 2022 | | Andrology
What is sickle cell disease? Sickle cell disease (SCD) is one of the most common single-gene disorders in the UK affecting approximately one in every 2000 live births. Approximately 20-25 million people worldwide have SCD. It predominately affects those of...

LUTS update

8 January 2024 | | Functional Urology
Case study A 70-year-old, generally fit and well male attends your outpatient clinic. He has experienced a gradual deterioration in his voiding over the last few months. Specifically, he reports hesitancy, poor flow and nocturia. He denies visible haematuria. His...

Benign prostatic hyperplasia: what are the benefits and harms of various surgical management options?

9 March 2020 | | Functional Urology, Infection, Neurourology, Technological Developments
Benign prostatic hyperplasia (BPH) is characterised by stromal and epithelial prostatic cell hyperplasia. The enlarged prostate may be associated with voiding and storage lower urinary tract symptoms (LUTS). These have been predominantly attributed to bladder outlet obstruction (BOO), assumed to...

Peyronie’s disease: a review and update

1 September 2017 | | Andrology
Peyronie’s disease (PD) describes an acquired disease of the penis, which is characterised by a number of signs and symptoms. These include penile pain, curvature, palpable plaques, wasting or narrowing of the penile shaft, a hinge deformity and potentially catastrophic...

Ejaculatory dysfunction: a review of current practice and guidelines

1 January 2015 | | Andrology
Introduction The ejaculatory process is paramount to procreation in nature. It is a complex orchestration of physiology that results in emission of the ejaculate into the posterior urethra followed by ejection of those fluids from the urethra and orgasm. The...