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Urethral pain syndrome – is there a light at the end of the tunnel?

1 September 2014 | | URO - Functional / Reconstructive Urology
Urethral pain syndrome (UPS) is defined in the 2014 EAU Guidelines as the occurrence of chronic or recurrent episodic pain perceived in the urethra, in the absence of proven infection or other obvious local pathology. UPS is often associated with...

Priapism

7 January 2021 | | URO - Andrology
Priapism is defined as an abnormally persistent erection lasting greater than four hours, not associated with sexual desire [1]. Although relatively uncommon with an incidence of 1.5 per 100,000 [2], priapism has a risk of complications which can have a...

Ipsilateral ureteroureterostomy: does function of the obstructed moiety matter?

1 September 2019 | | URO - Paediatrics, URO - Functional / Reconstructive Urology
Upper pole nephrectomy has been the traditional surgical management of children with poorly functioning upper pole moieties in duplex renal collecting systems having ureteral ectopia and ureterocele. However, ablative surgery confers a risk of functional loss to the remnant moiety...

Burnout in surgery

5 May 2021 | | URO - Core Urology
When I was pregnant with my first child, I went to a talk on how to achieve work-life balance and avoid burnout. It was given by a highly respected Australian surgeon and I was eager to hear the secrets that...

Prostate cancer

1 July 2015 | | URO - Urologic Oncology
Case 1 What is prostate specific antigen (PSA) and what is its function? According to the ERSPC Trial (at 13 years), what was the number needed to screen and diagnosed to prevent one prostate cancer death and what was the...

Dietary citrate substitution in urolithiasis patients

1 July 2018 | | URO - Endourology & Stones
Stone formation is dependent on supersaturation of urinary salts and urinary crystal retention. Urinary promoters (protein aggregates, cell debris) and inhibitors (citrate, magnesium, urinary macromolecules such as glycosaminoglycans and proteins) are involved in the process of stone formation [1]. Hypocitraturia...

A greener urology

13 August 2020 | | URO - Technology
Healthcare in England is responsible for 4-5% of the country’s carbon footprint which is defined as the amount of greenhouse gasses, primarily carbon dioxide, released into the atmosphere by a particular activity. The six greenhouse gasses which vary in their...

Urolithiasis 1 – ureteric colic

7 January 2026 | | URO - Endourology & Stones, URO - Uroradiology
- Click for Part 2 on this topic - Case scenario A 45-year-old male presents to Accident & Emergency with two days of intermittent, severe, left-sided loin to groin pain and multiple episodes of vomiting. He undergoes imaging as part...

Intravesical glycosaminoglycan analogue instillations for recurrent cystitis

1 May 2017 | | URO - Infection, URO - Functional / Reconstructive Urology
Introduction The symptoms of recurrent cystitis can be triggered by inflammatory or infective causes. Bladder pain syndrome (BPS) and bacterial recurrent lower urinary tract infection can both present with symptoms of recurrent cystitis and cause significant morbidity in affected individuals....

Endoscopic management of upper tract urothelial carcinoma

1 January 2014 | | URO - Urologic Oncology
Upper tract urothelial carcinoma (UTUC) is a rare disease accounting for 5-10% of all urothelial carcinomas and has an annual incidence in Western countries of 1-2 per 100,000 [1,2]. It occurs more commonly in the pelvicalyceal system as opposed to...

Intravesical GAG replacement therapies for bladder pain syndrome / interstitial cystitis – an update

4 May 2020 | | URO - Functional / Reconstructive Urology, URO - Infection, URO - Basic Science Research
The barrier function of the glycosaminoglycan (GAG) layer of the urothelium was identified by Parsons in 1975, and intravesical therapies to treat chronic inflammatory conditions of the bladder were developed soon after. However, the active role of the urothelium in...

Botulinum toxin – from the sausage poison to urology

4 May 2023 | | URO - Functional / Reconstructive Urology, URO - Infection
Botulinum toxin is the first biological toxin to be licensed for use in treating human disease and since its first therapeutic use in the early 1980s for strabismus has become widely used in the fields of ophthalmology, cosmetic surgery, migraine...