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The case against omitting systematic biopsy in younger men

In this issue of European Urology, Al-Monajjed et al. report findings from the PROBASE trial, which evaluated prostate cancer (PC) detection in men aged 45–50 years with PSA ≥3ng/ml using both MRI-targeted biopsy (TBx) and systematic biopsy (SBx). Among 525...

Is it time for a kidney stress test?

In healthcare, what we measure shapes how we predict outcomes and intervene. For kidney health, traditional tools like estimated glomerular filtration rate (eGFR) provide only a partial picture. Relying solely on eGFR is like judging heart health with a resting...

Urology Unboxed: A guide for aspiring urology residents

Urology Unboxed was a delightful read. It is a comprehensive guide for resident and future resident urologists who seek a structured and in-depth insight into common urological presentations. This easy-to follow handbook encompasses everything that a resident surgeon would require...

RSM: Andrology update 2026: advances across benign and oncological practice

Why attend? Hear from leading experts including Professor Axel Heidenreich, Professor Robert Huddart, Professor Vaibhav Modgil and Professor Nicholas Watkin Gain updates on advances in erectile dysfunction management, Peyronie’s disease and other benign andrological conditions Gain an up-to-date understanding of...

Precision ART: Insights into ICSI and Embryo Biopsy

Course description The microscopic treatment of individual eggs, sperm, or embryos to improve fertilization and pregnancy rates is an essential skill for an embryologist and is critical in achieving the best clinical outcomes. With a focus on ICSI and biopsy...

Metabolic screening and stone-prevention in urolithiasis patients

The incidence and prevalence of kidney stones is increasing [1,2]. Significant recurrence rates are noted with 14% of patients experiencing a further episode at one year, 35% at five years, and 52% at 10 years [3]. Over 10% of stone...

Practising surgery in a war zone: an interview with Dr Volodymyr Melnyk

It is now nine months since the full-scale Russian invasion of Ukraine commenced in late February 2022, with Putin announcing a “special military operation” to “denazify and demilitarise” Ukraine. The rest of the world, however, saw it for what it...

Orchid: fighting male cancer for over 25 years

Orchid was established in 1996 by a young testicular cancer patient, Colin Osborne MBE, and the oncologist who saved his life, Professor Tim Oliver MD, FRCP. The charity exists to save men’s lives from testicular, penile, and prostate cancers and...

Ambient scribes: the silent revolution

Clinical practice is in the midst of a profound digital transformation with a new wave of technology gaining increasing prominence: ambient scribes. These AI-powered tools streamline documentation by converting doctor–patient conversations into structured clinical notes in near real time. Healthcare...

Retroperitoneal sepsis

Case 1 An 80-year-old woman presented with history of recurrent and recent cystitis, low grade pyrexia, abdominal and back pain, and pain on movement of the left hip which was observed to be flexed and externally rotated. What is the...

Benign upper tract abnormalities

Case 1 A 28-year-old lady has been referred to your clinic with right loin pain. She has no significant past medical history but mentions that she and her partner have been trying to get pregnant. She has an US renal...

Infections and inflammation: Part 2

See also Part 1 and Part 3. Case 1 A 43-year-old lady presented to the urologist with a history of pain during bladder filling and associated frequency / urgency. She underwent standard microbiological and radiological investigations that are normal. She...