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Boosting the immune response to Bacillus Calmette-Guérin
In this issue of European Urology, Buisan et al. report early clinical and immunological outcomes of subcutaneous priming with the non-live mycobacterium tuberculosis RUTI vaccine prior to intravesical Bacillus Calmette-Guérin (BCG) in patients with non-muscle-invasive bladder cancer (NMIBC). The phase...
PARP inhibitors and prostate cancer
The discovery that BRCA1/2-deficient tumour cells are highly sensitive to poly-ADP ribose polymerase (PARP) inhibitors (PARPi) established the foundation of synthetic lethality in metastatic castration-resistant prostate cancer (mCRPC). The TOPARP-A trial confirmed clinical benefit, with PARPi activity largely restricted to...The scent of Ethiopia: a personal story part 2
In May/June 2016 we featured a wonderful account of Zeeshan Aslam’s first trip with Urolink to the Hawassa Referral Hospital in Ethiopia (see here). One year on we are delighted that Zeeshan has once again taken the time to provide...Creating online medical videos
Equipment When starting out with creating video content it can be overwhelming ensuring you have the right technology to help you create the best content. The truth is most of us have all we need in our pocket every day....Urology Podcasts and NotebookLM
Podcasts, downloadable or streamable digital audio / video shows, have surged in popularity over the last five years due to the ubiquity of smartphones, high-speed mobile networks, and accessible content creation technology. They offer on-the-go access to expert discussions, clinical...Action Bladder Cancer UK – 2019 Report
ABC UK is a national charity working for bladder cancer patients. Set up in 2009 we work to raise awareness of bladder cancer and the issues faced by patients; we provide direct support for patients; we work to improve outcomes for...Sustainable healthcare: what steps can urologists take?
Human health is intrinsically linked to environmental health, making the ever-pressing climate crisis fundamentally a public health emergency. The healthcare sector is responsible for 8% of the UK’s greenhouse gas (GHG) emissions worldwide [1]. As the largest publicly funded healthcare...
Long-term oncologic outcomes of salvage cryoablation for rrPC
Of patients undergoing radiotherapy (RT) for prostate cancer (PC), at least 15-20% will experience recurrence. Although salvage prostatectomy achieves durable oncological outcomes at 10 years, it is associated with significantly high morbidity. Thus, the majority of men with radio-recurrent prostate...Artificial intelligence
Artificial intelligence concerns me. Generally, people still tend to be concerned that their livelihoods will be replaced by an all powerful, all knowing artificial intelligence (AI) system. This at a time when the world’s largest technology companies (Amazon, Google, Apple),...
Textbook of the Neurogenic Bladder (Third Edition)
The third incarnation of this popular tome remains as imposing as ever. However, it has less the feel of an encyclopaedia about it than one might initially have feared. Whilst there is clearly some very great detail here – with...
Urinary Stones – Medical and Surgical Management
This book is nicely adapted to cover both the medical and surgical management of urinary stone disease. Those chapters dealing with the surgical management of stone disease are dealt with unsurprisingly well – delivered with a relaxed and conversational prose...
