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Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer
Abiraterone acetate, the prodrug of abiraterone, blocks endogenous androgen synthesis by inhibiting cytochrome p-450c17, a critical enzyme in androgen biosynthesis. Its active D4A metabolite also has anti-tumour effects through possibly multiple mechanisms. 3-5% of men diagnosed with prostate cancer in...EMS Flexible Ureteroscopy and Percutaneous Surgery Masterclass
The Masterclass comprises a combination of didactic presentations, as-live surgery presentations, and live case observation on surgical techniques, tips and tricks, and the medical management of stone patients.EMA Stone management with Endoscopic Combined Intrarenal Surgery (ECIRS)
The Masterclass comprises a combination of didactic presentations, as-live surgery presentations, and live case observation on surgical techniques, tips and tricks, and the medical management of stone patients.EMS Stone management with Endoscopic Combined Intrarenal Surgery (ECIRS)
The Masterclass comprises a combination of didactic presentations, as-live surgery presentations, and live case observation on surgical techniques, tips and tricks, and the medical management of stone patients.EMS Endoscopic Stone removal using Swiss LithoClast® Trilogy
The Masterclass comprises a combination of didactic presentations, as-live surgery presentations, and live case observation on surgical techniques, tips and tricks, and the medical management of stone patients.HIV / AIDS – implications for the urologist
“It’s no fun to have HIV even though it’s viewed as a chronic, controllable disease. It means being wedded to the health system.” - Philip Berger, Associate Professor in the Department of Family and Community Medicine, Toronto, Canada; and leading...Urinary biomarkers for surveillance of non-muscle invasive bladder cancer
Bladder cancer (BC) is the ninth most common cancer worldwide with a yearly incidence of approximately 430,000 cases. There is a male predominance and it is the seventh most common cancer in men worldwide [1]. Non-muscle invasive bladder cancer (NMIBC)...History of prostate biopsy – part 2
For Part 1 of this topic is available here. The major limitations of the transrectal ultrasound (TRUS) guided prostate biopsy (PBx) protocols are the risk of profound sepsis and the risk of persistently significant false negative rates, related to the...
Fluoroquinolone resistant rectal colonisation predicts risk of infectious complications after TRPB
Transrectal prostate biopsy (TRPB) has been associated with increased risk of infection between 3.6-5% and sepsis rates of 0.3-3.1% mainly due to fluoroquinolone resistance (FQR). At present, FQ antibiotic prophylaxis is utilised commonly across North America and Europe but due...
