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A phase II dose-ranging study of mirabegron in patients with OAB
This was a multinational, multicentre, randomised, double–blind, double-dummy, parallel group placebo- and active- controlled phase II study. The study enrolled 1108 men and women aged 18 and over. The criteria were: patients must have had overactive blader (OAB) symptoms for...
Psychosocial and sexual outcomes after surgery for proximal hypospadias
Andersson et al. report the psychosocial and sexual outcomes for adolescents treated previously for proximal hypospadias. They hypothesised outcomes would be negatively affected compared to patients with distal hypospadias or age-matched controls (Swedish population registry). Participants answered a web-based questionnaire...
Telemedicine – safe, convenient and economical
I am sure that most, if not all, readers of Urology News will have utilised some form of telemedicine over the last few months during the height of the COVID-19 pandemic. This timely publication from Boston Children’s Hospital precedes the...
Would some boys undergoing orchidopexy benefit from adjuvant hormonal therapy?
Orchidopexy is generally recommended between six months and one year of age given that many studies have shown that there is a progressive histological deterioration and poorer growth of the undescended testis that is not brought down to the scrotum...
Delayed decompression of the infected obstructed kidney increases fatality
Well, we know this, I hear you all say. It is standard practice that the obstructed kidney with associated infection requires prompt decompression, and this is drilled into all UK trainees. It is surprising therefore that although we frequently deal...
Cardiac failure and medical therapy for LUTS / BPH
Alpha blockers (AB), 5-alpha reductase inhibitors (5-ARI) and combination therapy are widely prescribed for lower urinary tract symptoms (LUTS) considered consequent to prostatic enlargement and are the mainstay of first-line therapy. This retrospective interrogation of a large population-based dataset of...Prostate Cancer UK warns of over 8,600 ‘missing men’ as referrals drop by 52,000
The Covid-19 pandemic has led to around 52,000 (28%) fewer urgent prostate cancer referrals in England alone, according to statistics shared by Prostate Cancer UK. It’s estimated that more than 8,600 fewer men started treatment for...Bupa covers accurate PSE prostate cancer blood test
A new era in prostate cancer detection is emerging with the EpiSwitch® PSE blood test, a highly accurate tool that enhances early diagnosis while significantly cutting false positives. Now covered by Bupa as a pre-biopsy test, PSE has demonstrated 94%...Medical Protection: Expertise, advocacy, and support when it matters most
The world’s leading medical defence organisation providing long-term protection against the potentially ruinous costs of litigation, as well as the other professional challenges that healthcare professionals might face during the course of their career. As a doctor your work is...
