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Results from the REDUCE study
Subjects in this paper were part of the Reduction by Dutasteride of PCa Events (REDUCE) study, a clinical trial enrolling men who had undergone a single negative prostate biopsy within six months of enrollment and subjecting them to a repeat...
Near-infrared fluorescence in robotic surgery
This is a systematic review and critical analysis of the current evidence on the applications of near-infrared fluorescence (NIRF) in robotic urologic surgery. It uses indocyanine green (ICG), a sterile water-soluble dye which has been tested in various fields. In...
Comparison of PCNL under spinal versus general anaesthesia
There are several advantages of performing percutaneous nephrolithotomy (PCNL) under spinal anaesthesia including lower cost, reduced adverse effects and less tracheal tube displacement. Another advantage is that the patient remains awake throughout making positioning easier and reducing the risk of...
A phase II dose-ranging study of mirabegron in patients with OAB
This was a multinational, multicentre, randomised, double–blind, double-dummy, parallel group placebo- and active- controlled phase II study. The study enrolled 1108 men and women aged 18 and over. The criteria were: patients must have had overactive blader (OAB) symptoms for...Prostate Cancer UK warns of over 8,600 ‘missing men’ as referrals drop by 52,000
The Covid-19 pandemic has led to around 52,000 (28%) fewer urgent prostate cancer referrals in England alone, according to statistics shared by Prostate Cancer UK. It’s estimated that more than 8,600 fewer men started treatment for...Prostate Scotland’s COMPASS Impact Report highlights how men in Scotland are benefiting from prostate cancer support services
Prostate Scotland has published its COMPASS Impact Report 2020-2024, providing a detailed account of how its support services are improving outcomes for men living with prostate cancer across Scotland. Developed to complement care provided by clinical teams, COMPASS helps men...Purple urine bag syndrome
Purple urine bag syndrome (PUBS) is an uncommon phenomenon where the tubing and urinary catheter bag is noticed to undergo purple discolouration. This has been linked with urinary tract infections (UTI), chronic debilitated states and prolonged catheterisation. PUBS was noticed...
Prostatic urethral lift provides good alternative to TURP for men with LUTS
Lower urinary tract symptoms (LUTS) due to prostatic enlargement resulting in bladder outflow obstruction are common. Transurethral resection of the prostate (TURP) remains the gold standard in operative management, however it is not without its risks. In this multicentre European...
Fluoxetine for refractory night wetting in children – is it safe and effective?
Around 1-2% of teenagers above the age of 15 years and 2-6% of adults continue to wet the bed. Standard treatment often includes bladder advice, alarm therapy, desmopressin and anticholinergics. Tricyclic antidepressants (imipramine) can also be utilised. Unfortunately, most have...
Is transperineal prostate biopsy without antibiotic prophylaxis the new gold standard?
Prostate cancer is the second most diagnosed malignancy among men worldwide. Despite substantial advances in MRI–guided diagnostic pathways, prostate biopsy with histopathological evaluation remains indispensable for definitive diagnosis. Historically, transrectal biopsy (TRBx) has been the standard approach; however, concerns regarding...Inguino-scrotal sarcomas
A sarcoma is a malignant tumour that originates from mesenchymal cells such as adipose tissue, bone, cartilage and smooth muscle. Although these tumours histologically do not originate from the urogenital tract, urologists are often involved in their diagnosis and management...
