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Biomarkers in prostate cancer detection

1 July 2018 | | URO - Basic Science Research, URO - Urologic Oncology, URO - Technology
Prostate cancer (PCa) is the second most common cancer in men with an estimated prevalence of 1.1 million worldwide in 2012. This heterogeneous disease resulted in approximately 307,000 deaths, making it the fifth leading cause of cancer-related death in men...

TIP hypospadias repair

1 July 2016 | | URO - Paediatric Urology
This paper by one of the current international leaders in hypospadias surgery looks at the outcome of over 1800 consecutive hypospadias repairs using the tubularised incised plate (TIP) repair, beginning from the first original operation through to sequential modifications over...

Renal masses

2 March 2022 | | URO - Urologic Oncology
Case 1 A 70-year-old female presented under the medical team with malaise, weight loss, and deranged liver function tests (LFTs) and calcium (ALP 350, GGT 650, Serum bilirubin 29, normal aminotransferases, Ca 3.3). An abdominal ultrasound scan (USS) was performed...
The Journal of Urology cover image.

Hypospadias – how long should follow-up be?

3 February 2023 | | URO - Paediatric Urology
The optimal duration of follow-up following childhood hypospadias repair (to detect complications) is ill-defined. Several surgeons recommend it to include assessment during puberty. Some may worry that ‘rapid penile growth’, ‘erectile forces’ and ‘sexual activity’ could potentially stress previously successful...

The doctor as the patient: receiving bad news

13 March 2023 | URO - Urologic Oncology
This article, written by a GP working in the NHS, gives a unique insight into the experience of being a urology patient and some thoughtful advice on ‘breaking bad news’. Day 1 Alarm bells ring. It’s spotting an email from...

The role of PET-CT imaging in prostate cancer

4 October 2021 | | URO - Urologic Oncology
Prostate cancer (PCa) is the second most common cancer in the UK, with 43,000 cases in 2017-18 [1,2]. Accurate primary staging and the detection of suspected recurrence following treatment is vital for directing management and predicting prognosis. This has conventionally...

ICS updates in continence care: a personal perspective on the role of basic science in urology

1 March 2017 | | URO - Basic Science Research, URO - Functional / Reconstructive Urology
At a urology research meeting in Sheffield a few years ago, a former post doctorate researcher in urology, Mathieu Boudes, said: “Stop calling it basic research, there is nothing basic about it. It is fundamental research to everything urologists do.”...

ICS updates on continence care: making sense of detrusor underactivity and the underactive bladder

1 July 2016 | | URO - Functional / Reconstructive Urology
Countless epidemiological studies have established the frequent occurrence of lower urinary tract symptoms (LUTS) and the significant burden these symptoms incur. For the most part of the past three decades, there has been an overwhelming focus on detrusor overactivity (DO)...

Mechanisms and prevention of catheterisation associated urethral injury (CAUI)

5 November 2019 | | URO - Neurourology, URO - Infection, URO - Functional / Reconstructive Urology, URO - Technology
Urethral catheterisation is a common procedure performed by health professionals across different grades and specialties in a variety of clinical settings. An estimated 15-25% of hospitalised patients have a urinary catheter inserted during their inpatient stay and up to 13%...

Klinefelter’s syndrome

7 January 2020 | | URO - Andrology, URO - Basic Science Research, URO - Paediatric Urology
Klinefelter’s syndrome (KF) is the most frequent sex chromosome abnormality with an estimated prevalence of 1 in 500 to 1 in 700 newborn males and 1 in 10 in men with azoospermia. While the majority of cases are an XXY...

Metabolic screening and stone-prevention in urolithiasis patients

1 July 2017 | | URO - Endourology & Stones
The incidence and prevalence of kidney stones is increasing [1,2]. Significant recurrence rates are noted with 14% of patients experiencing a further episode at one year, 35% at five years, and 52% at 10 years [3]. Over 10% of stone...

Urologic complications of radiotherapy

1 July 2014 | | URO - Urologic Oncology
Case 1 1. What machine is seen in the picture? 2. What is the standard dose schedule for radiotherapy for prostate cancer? 3. What are the complications of radiotherapy? Case 2 1. How does haemorrhagic cystitis develop? 2. What are...