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Understanding gender differences in nephrolithiasis
Rates of nephrolithiasis are higher in males than females. The cause for this remains unclear, however animal models have demonstrated an association between sex steroid hormone levels and lithogenesis. This relationship in humans is less well established. This study from...
Factors associated with post ureteroscopy urosepsis
The authors investigate which factors were most likely to increase the risk of postoperative urosepsis within 28 days of ureteroscopy (URS) and laser stone fragmentation by analysing the 34 of 562 patients who developed this complication. Stone size, same session...
Effect of collimation on radiation dose during ureteroscopy
Over 60,000 ureteroscopies are performed annually in the UK. During these procedures radiation is used and there are concerns regarding the cumulative dose during a surgeon’s career. Common ways to minimise the dose to the theatre team are wearing lead...
Kidney stone basketing forces unmasked
Ureteral avulsion is the most dreaded situation for any urologist to be faced with. Although uncommon, with rates of ureteroscopy on the increase, the potential for this serious complication should also be recognised. To avoid such serious complications, smart devices...
Renal stones: an American perspective
This study is from Dallas, USA and appears on the front cover of the BMJ. About 1 in 11 people will have a kidney stone at some point in their lifetime. There is a linear increase in stone prevalence in...
Sepsis and antibiotics: the debate goes on
Sepsis statistics are staggering around the world. The UK Sepsis Trust estimates that there are around 150,000 cases of sepsis in the UK every year and it kills 44,000 patients per year. There are many different definitions and criteria; in...
Tolerability and persistence in women prescribed mirabegron
Mirabegron is a beta-3 agonist used in the treatment of overactive bladder (OAB). Trials have shown reduced side-effects but equal efficacy when compared to anticholinergics. The authors wished to examine patients’ persistence with treatment, in a non-trial setting, over a...
How effective are intravesical therapies for bladder pain syndrome?
The objective of this study was to review the clinical efficacy of currently available products for the intravesical treatment of bladder pain syndrome (BPS) / interstitial cystitis (IC) and to assess their pharmaco-economic impact. Nineteen articles were reviewed, including five...
Do complementary therapies work in painful bladder syndrome?
The aim of this systematic review was to evaluate the effectiveness of complementary therapies in the treatment of bladder pain syndrome. An electronic search identified 1454 articles; however, after review by two independent reviewers, this was reduced to 11 articles...
Surgical management of urethral diverticula in women
This systematic review aimed to evaluate different surgical techniques and their outcomes used for treating women with urethral diverticulae. One hundred and eight studies were identified; some of these however were single case reports (37%). As one would expect the...
Cord compression in cancer
This article will be of great interest to uro-oncologists. Vertebral metastasis occurs in 3-5% of all cancers (most commonly in prostate, breast and lung cancer). It can cause pain, vertebral collapse and cord compression. Data from the National Institute for...
