You searched for "patient"
PARP inhibitors and prostate cancer
The discovery that BRCA1/2-deficient tumour cells are highly sensitive to poly-ADP ribose polymerase (PARP) inhibitors (PARPi) established the foundation of synthetic lethality in metastatic castration-resistant prostate cancer (mCRPC). The TOPARP-A trial confirmed clinical benefit, with PARPi activity largely restricted to...Andrology (2020)
Case 1 What is the diagnosis based on the blood test, and how is the diagnosis made? What additional blood tests are required? What are the clinical manifestations of this? What are the options / modes of delivery for treatment?...The transition from surgeon to manager during the COVID-19 response
Writing this article on the first Sunday in May, when in any other year, I would be wearing my bowler hat in Hyde Park for the annual Cavalry Memorial Parade, a time ‘pre-COVID’ does seem a very distant memory. Having...Lasers in urology
1. What does LASER stand for? 2. What elements are involved and how is a LASER created? 3. The following cases involve laser surgery. Can you diagnose the pathology, identify which type of lasers can be used, and their wavelengths?...Urolithiasis 3 – renal stones and ureteroscopy
- Click for Part 1 and Part 2 on this topic - Case scenario A 36-year-old man with a known renal stone attends your stone clinic following a surveillance CT KUB with worsening intermittent right flank pain. Figures 1 and...Becoming a consultant: Navigating the next step in your career
For senior urology trainees approaching their final ARCP, one question often looms large: what next? Some pursue a fellowship, while others may take some time out. Ultimately, however, all trainees face the inevitable transition: stepping into a consultant post. This...Sexually transmitted infections
Case 1 A 27-year-old man presents to the clinic with multiple asymptomatic penile lesions. 1. What is the diagnosis? 2. What are the likely pathogens which cause these lesions? 3. What treatment options are available to treat these lesions? 4....An overview of non-surgical treatment options for Peyronie’s disease
Peyronie’s disease (PD) is a therapeutic challenge despite the availability of several non-surgical and surgical options. Very few of these options are supported by good quality evidence according to the current American and European guidelines [1-3]. The period of plaque...A time management guide for urologists
Good time management is thought to not only reduce stress, but to improve personal efficiency, service delivery, clinical effectiveness and patient care. It was Benjamin Franklin in the 18th Century who originally made the link between success and the proper...SURG and BAUS: United Strength is Stronger
Tuesday 26 June 2018, SURG Session, BAUS Annual Conference, Liverpool After a busy day of posters, keynote speakers, e-poster sessions and a resounding victory for the SURG team over the consultants in Urology University Challenge, came the SURG meeting. An...
Surgery in disorders of sexual development with gender issues
After the initial consensus meeting of 10 years ago on disorders of sex development (DSD) with the introduction of the new terminology and classification there are still abundant controversial issues associated with the management of children with these conditions. This...
