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1268 results found

Predicting bone scan positivity in non-metastatic CRPC

There is evidence that suggests that early treatment with chemotherapy, immunotherapy or hormone therapy leads to a better response in patients with asymptomatic metastatic castrate resistant prostate cancer (CRPC). This study aimed to predict bone scan positivity in patients with...

The potential of statin use in castrate resistant prostate cancer treatment

One of the mechanisms by which prostate cancer achieves castrate resistance is through de novo intratumoral production of androgens. Reactivation of androgen receptors results in promotion of cell survival and proliferation pathways despite castrate serum testosterone levels. As androgen synthesis...

Metabolic syndrome and prostate cancer recurrence in a veterans’ cohort

This study explored the relationship between metabolic syndrome and localised prostate cancer recurrence in patients who had received active treatment (external beam radiation therapy – EBRT, radical retropubic prostatectomy – RRP, or brachytherapy). The definition of metabolic syndrome adopted was...

Penile clamp device – a new indication?

This study originates from New Zealand and looks at men affected by post-prostatectomy incontinence (PPI). These patients are difficult to manage with the options of further surgery, indwelling catheters or pads. The aim of this questionnaire study (IIQ 7) was...

Screening tool for incontinence: Michigan index

The Michigan incontinence symptom index (MISI) is a validated measure. This study further evaluated its relevance. MISI is a 10-item measure; MISI domain 1-8 and bother domain 9-10. Two hundred and fourteen women were included in the study, with a...

Bladder cancer diagnosis and follow up: A new proven urinary biomarker to support the post COVID-19 recovery phase

Since lockdown began most urologists have been following the advice of BAUS Oncology, to minimise the risk of exposure of patients and staff to potential COVID-19 infection: the result is an increasing backlog of patients requiring tests to determine if...

New senior appointments at The Urology Foundation

The Urology Foundation (TUF) has appointed Rebecca Porta as Chief Executive. An established and experienced charity Chief Executive, Rebecca brings a wealth of experience having held senior roles within some of the UK’s leading health and medical research charities.

Surgeons take to the saddle for ninth annual Bike4TUF fundraiser

This year marks the ninth annual Bike4TUF challenge, which has raised in excess of £300,000 since 2012’s inaugural ride.

NICE has recently moved the IRE guidelines from ‘Research Only’ to ‘Special Arrangements’

This recent update provides increased access to the AngioDynamics NanoKnife IRE ablation...

Campbell Walsh Wein Urology: 3-Volume Set (Campbell-Walsh Urology), 12th Edition

The 12th edition of the ‘Bible of Urology’ was a pleasure to review. The title has been changed to Campbell-Walsh-Wein Urology to honour Dr Alan Wein’s many years of dedicated chief editorship of this famous textbook. The current editor-in-chief, Alan...

Scrotal antegrade sclerotherapy for the adolescent varicocele

The incidence of varicocele in adolescent males is around 15%. Treatment indications include symptoms (pain) and evidence of a smaller testis. Numerous surgical techniques are described but there is a lack of randomised controlled trials (RCT), specifically in adolescents. This...

Intravesical cytosine arabinoside + Mitomycin C for bladder cancer – is it beneficial?

Mitomycin C (MMC) is often used as an intravesical therapy for low / intermediate risk non-muscle invasive bladder cancer. This randomised controlled trial (RCT) was designed to assess the safety and efficacy of MMC + cytosine arabinoside (Ara-C). Ara-C was...