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Importance of PSA variation – an analysis of PLCO trial data
This study looks specifically at the group of patients in the intervention arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening trial (PLCO), to investigate variations in prostate specific antigen (PSA) level. They have specifically included only patients who...
Phase two trial of SAbR for primary RCC
A study focused on stereotactic ablative radiotherapy (SAbR) as a treatment for primary renal cell carcinoma (RCC) has yielded significant findings. The primary objective of the study was successfully met, demonstrating a 94% local control rate at one year among...
Changing concepts in endourological training – SIMULATE trial
Skill acquisition for endourological procedures is markedly different from traditional open surgical procedures, questioning the applicability of the presently used apprenticeship model. The lack of a universal simulation training curriculum has hampered its adoption into mainstream urological training. This study...
Optimisation of childhood spina bifida management – a prospective trial
Routh et al. describe a prospective trial which aims to determine the optimal urological management for children with spina bifida. The primary aim of neuropathic bladder management is to provide the patient with the best long-term quality of life with...
To clamp or not to clamp – outcomes of the CLOCK trial for robotic partial nephrectomy
The benefits of partial over radical nephrectomy are well established. The CLOCK trial (CLamp vs. Off Clamp the Kidney during robotic partial nephrectomy) was designed as a multicentre, randomised controlled trial to generate evidence on the role of the off-clamp...The PROMIS trial – time for multi-parametric MRI before a first prostate biopsy
Whilst the relatively random process of 12 core transrectal ultrasound guided (TRUS) prostate biopsy remains by far the most widely employed approach to prostate cancer diagnosis in the UK, its flaws as a standalone diagnostic strategy are increasingly apparent. TRUS-biopsy...
Evaluation of a web-based eHealth programme for children with urinary incontinence: eADVICE Trial
Long waiting times for specialist urology outpatient clinics for children are frustrating for both parents and health practitioners. Delays may result in a deterioration in health and quality of life. Electronic Advice and Diagnosis Via the Internet following Computerized Evaluation...Femeda commence innovative real world clinical trial for Pelviva
A major 330 patient randomised ‘real world’ clinical trial has commenced for Pelviva in conjunction with the University of Manchester and South Manchester GP federation. The trial will compare Pelviva against...EAU (European Association of Urology) Talent Incubator Programme: Policy & Innovation
The randomised controlled trial (RCT) will remain one of the most important methods for medical advancements. A solid framework, an extensive network and financial resources are key factors in the success of a trial. In this module of the Talent Incubator Programme, we will address the practical side of conducting research and trials with support from policy experts, industry representatives and patient advocates
PTNS in overactive bladder
This article will be of interest to those who undertake percutaneous tibial nerve stimulation (PTNS) or are planning to start doing so. This is a computer aided search between 2000-2011 to identify randomised controlled trials (RCT), controlled clinical trials (CCT)...
